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Everything You Want to Know About Beta Thalassemia

Posted on 08/13/2020 by Finding Doc

Thalassemia is an inherited blood disorder. This means that it passed down to the offspring from the parents through their genes. If you suffer from Thalassemia, your body makes less haemoglobin than usual. Haemoglobin is an iron-rich protein produced by red blood cells. This protein helps in carrying oxygen to all parts of the body.

Thalassemia is classified in two ways: alpha and beta. Various genes are affected by each type. Thalassemia can result in mild or severe anaemia. Anaemia usually develops when the body does not have enough red blood cells or haemoglobin.

How much severe or what type of anaemia, you will develop will depend on how many genes are affected. Get beta-thalassemia treatment, if you have found out that your child is suffering from it.

What Causes Beta Thalassemia?

Beta thalassemia is caused by Mutations in the HBB genes. HBB genes give instructions for making a protein called beta-globin.

Types of Disorder are:

Beta thalassemia major (Cooley’s anemia): Here, there are two damaged genes. Out of the different types, this is the most severe form of this disorder. For best thalasemmia treatment in Delhi, you should visit a hospital because you may need frequent blood transfusions. People having this form of beta-thalassemia, may not live an average lifespan.

Beta thalassemia minor or thalassemia trait: In this type, only one gene is damaged. This results in less severe anemia. Children have 50 per cent chances of getting it from their parents. Even if the other parent is not affected, their children will have this form of the disorder. This type is further divided into:

  • Thalassemia minima: There are less or no symptoms.
  • Thalassemia intermedia: This results in moderate to severe anemia.

For the best thalasemmia treatment in Gurgaon, visit the best doctor because many people with this disorder are given iron replacement by mistake. But too much iron is harmful. So, it’s essential to get the correct diagnosis. Call a haematologist or blood specialist for your treatment.

Who is at Risk for Beta Thalassemia?

As Beta thalassemia is a genetic disease which is inherited from one or both parents. People having a family history of the disease are the risk factor.

Symptoms of beta thalassemia

Different people will observe various symptoms, based on which type of disorder they have inherited. For best thalasemmia treatment in Noida, you should visit a specialist to determine which type of Thalassemia you have inherited.

Beta thalassemia major: This is the most serious type of this disorder. Any children suffering from this disorder will have symptoms such as,

  • Pale skin
  • Fussy
  • Having a poor appetite
  • Having many infections

Over time other symptoms may appear, including:

  • Slowed growth
  • Belly (abdominal) swelling
  • Yellowish skin (jaundice)

Without thalassemia treatment, the spleen, liver, and heart become enlarged. It also affects bones which may become thin, brittle, and deformed. People suffering from this condition will need frequent blood transfusions and may not live a regular life. Due to blood transfusions, iron builds up in the heart and in other organs. This can results in heart failure as early as the teens or early 20s.

Thalassemia minima: This type generally causes no symptoms.

Thalassemia intermedia: Symptoms ranging moderate to severe anemia may include:

  • Extreme tiredness (fatigue)
  • Pale skin
  • Slow or delayed growth
  • Weak bones
  • Enlarged spleen

Diagnosis of Beta Thalassemia

People who have Greek, Italian, African, or Asian ancestry usually develop Beta thalassemia. The diagnosis for beta thalassemia is often made between 6 and 12 years old.

Get yourself screened with these tests to see if you are a carrier, and can pass the disorder on to your children:

  • Complete blood count (CBC): This test checks the number, size, and maturity of different blood cells in a set volume of blood.
  • Haemoglobin electrophoresis with haemoglobin F and A2 quantitation: This test helps in differentiating the types of haemoglobin.

You don’t have to worry about giving a different blood sample; every study can be done from a single blood sample. To diagnose a baby in pregnant women, CVS (chorionic villus sampling) or amniocentesis test is used.

Beta Thalassemia Treatment

For best thalassemia treatment in Delhi, consult the best specialist who will determine the best Thalassemia Treatment for you depending on:

  • Your age, overall health, and medical history
  • How sick you are
  • How well you can handle specific medicines, procedures, or therapies
  • How long the condition is expected to last
  • Your opinion or preference

Treatment may include:

  • Regular blood transfusions
  • Iron chelation therapy where Medicines will reduce extra iron from your body
  • Surgery to remove the spleen, if needed
  • Daily folic acid
  • Surgery to remove the gallbladder
  • Regular checks of heart and liver function
  • Genetic tests
  • Bone marrow transplant